Hanna SEVERINA

Hanna SEVERINA

Hanna SEVERINA

Doctor of Pharmaceutical Sciences, Professor of the Department of Pharmaceutical Chemistry of the National University of Pharmacy

Address: Kharkiv 61170, Valentinivska str., 4

Tel.: (0572) 67-92-04

E-mail: severina.ai@ukr.net

Profile:

  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA

 

General information

Hanna Severina was born on August 19, 1983 in Cherkasy. In 2000, she graduated with honors from school №22 in Cherkassy and entered the National Pharmaceutical Academy, Faculty of Pharmacy. Starting from the 3rd year of studies at the University, Hanna was a member of the student scientific society of the department of pharmaceutical chemistry and, based on the results of research, defended her thesis on the topic ‘Synthesis of potential biologically active substances based on cyanoacetic acid benzylamide’. In 2005, she graduated from the National University of Pharmacy and was qualified as a pharmacist. Since 2005, she worked in pharmacy №183 in Kharkiv as a pharmacist-intern and a senior laboratory assistant at the Department of Pharmaceutical Chemistry. In 2006, she entered the postgraduate program of the National University of Pharmacy, Department of Pharmaceutical Chemistry. During her postgraduate studies, Hanna was actively engaged in scientific research, which was awarded by a scholarship of the President of Ukraine for young scientists.

In 2010, Hanna Severina defended her candidate’s thesis on the specialty 15.00.02 – pharmaceutical chemistry and pharmacognosy on the topic ‘Synthesis, physicochemical properties and anticonvulsant activity of 3-amino- and 4-amino-3-mercapto-1,2,4-triazole derivatives and products of their chemical transformations’ under the supervision of Doctor of Pharmaceutical Sciences, Professor V. A. Georgiyants.

In December 2006, Hanna Severina began her teaching activities at the Department of Pharmaceutical Chemistry of the National University of Pharmacy as an assistant, and in September 2012 she received the academic title of Associate Professor of the Department of Pharmaceutical Chemistry.

From 2018 to 2020, she was a doctorate at the Department of Pharmaceutical Chemistry.

On April 22, 2021, Hanna Severina defended the thesis for the degree of Doctor of Pharmaceutical Sciences, specialty 15.00.02 – pharmaceutical chemistry and pharmacognosy on the topic ‘Synthesis and physicochemical characteristics of central nervous system agents among pyrimidine-4-one and pyrimidine-2(4)-tion derivatives’ under the consultation of Doctor of Pharmaceutical Sciences, Professor V. A. Georgiyants.

On August 23, 2023, she received the degree of Professor of the Department of Pharmaceutical Chemistry.

Severina G.I. constantly improves her qualification, in particular, she passed the training cycles “Modern Teaching Technologies” (IATPS NUPh, Kharkiv, 2009), “Lecturing Skills of a Teacher” (IATPS NUPh, Kharkiv, 2012), “Information and Communication Technologies of Distance Learning: e-Tutor” (Institute of Master’s Training and Postgraduate Education, Kyiv, 2016). ), “Modern knowledge in medicine and pharmacy – the key to good pharmacy practice of a pharmacist” (Ukrainian School of Pharmacy, Kyiv, 2021), “The latest directions of development and improvement of the quality assurance system in pharmacy” (IATPS NUPh, Kharkiv, 2021), international internship at the Lithuanian University of Medical Sciences “Erasmus+, International Staff Week 2022” (LSMU, Kaunas, 2022).

In 2012, Hanna Severina graduated from the two-year foreign language courses of the Linguistic Center of the School of Foreign Languages of V.N. Karazin Kharkiv National University, and in 2022 received an international certificate confirming her knowledge of English at the B2 level (Universal Test, ECL Examination center, European Consortium for the Certificate of Attainment in Modern Languages).

Social activities

From 2009 to 2013 Hanna Severina performed the duties of secretary of the State Examination Commission of the Faculty of Pharmacy and continued this activity from 2017 to 2019. Since 2022, she has become a member of the Academic Council of the National University of Pharmacy. Member of the Expert problem commission of the NUPh (2024), expert of the National Agency for Quality Assurance in Higher Education (2024).

Scientific school

Hanna Severina’s scientific direction is rational molecular design of biologically active substances among azaheterocycles based on a combination of traditional organic synthesis and innovative technologies of virtual screening, molecular docking, and QSAR analysis; development and validation of quality control methods for promising APIs.

Since 2021, Hanna Severina is the head of research at the National University of Pharmacy, which is being carried out at the expense of the state budget on the topic ‘Synthesis and research of new thienopyrimidines for the detection of antimicrobial and related types of pharmacological activity’ (Order of the Ministry of Health of Ukraine dated 17.11.2020 No. 2651, term: 2021 -2023).

Under the supervision of Hanna Severina, a dissertation for the degree of Doctor of Pharmaceutical Sciences (doctoral student Serhii Plys).

In 2023, under the supervision of Hanna Severina, Wassim M. El Kayal, Lebanon, defended his dissertation for the degree of Doctor of Philosophy.

Since 2023, he has been a member of the editorial board of the professional scientific journal “Health & Education” (Ukraine) and a reviewer of the professional scientific journal “Social Pharmacy in Healthcare” (Ukraine).

Co-author of more than 130 scientific and educational works, including:

  • 42 scientific articles in specialized journals, of which 20 are indexed in the Scopus and Web of Science databases;
  • 16 scientific and methodical recommendations;
  • 16 patents of Ukraine;
  • 1 information letter about innovations in the area of health care;
  • more than 60 abstracts;
  • 5 training manuals with the seal of the Ministry of Education and Science of Ukraine, including 1 in English.

Textbooks

  1. Фармацевтична броматологія : навч. посіб. для студ. вищ. навч. закл. / В.А. Георгіянц, П.О. Безуглий, Н.В. Попова та ін. ; за заг. ред. В.А. Георгіянц. – Харків : НФаУ : Золоті сторінки, 2017. – 417 с.
  2. Фармацевтическая броматология : лекции / Н. В. Попова [и др.]. Н. В. Попова, П. А. Безуглый, В. А. Георгиянц, О. С. Головченко, Г. И. Северина, Г. П. Казаков, С. В. Ковалев, Д. А. Алферова – Х.: Изд-во НФаУ, 2015. – 160 с.
  3. Pharmaceutical bromatology: lectures for English-speaking students: the manual for students of higher schools / V. A. Georgiyants, P. O. Bezugly, G. O. Burian et al.; edited by V. A. Georgiyants. – Kharkiv: NUPh : Golden pages, 2015. – 368 p.
  4. Збірник тестів з фармацевтичної хімії : навч. посіб. для студ. вищ. навч. закл. / П.О. Безуглий, В.А. Георгіянц, І.С. Гриценко та ін. – 2-ге вид. – Х. : НФаУ, 2015. – 304 с.
  5. Фармацевтическая броматология : учеб. пособ. для студ. высш. учеб. заведений / В. А. Георгиянц, П. А. Безуглый, А. И. Северина и др.; под общ. ред. проф. В. А. Георгиянц – Х. : НФаУ, 2014. – 376 с.

Methodical guidelines

  1. Pharmaceutical chemistry : Collection of test tasks for preparation to the Unified State Qualification Exam STAGE 2 «Pharmacy»/ V. A. Georgiyants, L. V. Sydorenko, S. V. Vlasov, H. I. Severina, N. Yu. Bevz, H. O. Burian, N. V. Harna, O. S. Holovchenko, O. V. Gorokhova, L. O. Petrushova, N. M. Smielova, H. V. Hryhoriv, V. V. Hrynenko – Kharkiv : NUPh, 2024. – 91 с.
  2. Фармацевтична хімія : зб. тестових завдань для підготовки до ліцензійного іспиту Крок 2 «Фармація»/ В. А. Георгіянц, Л. В. Сидоренко, С. В. Власов, Г. І. Северіна, Н. Ю. Бевз, Г. О. Бур’ян, Н. В. Гарна, О. С. Головченко, О. В. Горохова, Л. О. Петрушова, Н. М. Смєлова, Г. В. Григорів, О. В. Колісник – перевид. і допов. – Харків : НФаУ, 2024. – 93 с.
  3. Pharmaceutical bromatology. Workbook for practical classes and individual work for students of speciality ‘Pharmacy, Industrial Pharmacy’ / V. A. Georgiyants, O. S. Holovchenko, O. V. Kolisnyk, H. I. Severina, N. M. Smielova, O. O. Mykhailenko, O. A. Yevtifieieva, H. V. Hryhoriv, V. A. Mishchenko. – H.: NUPh, 2023. – 37 p. (протокол ЦМР № 2 від 16.02.2023 р.)
  4. Фармацевтична броматологія. Робочий зошит для практичних занять та самостійної роботи для здобувачів вищої освіти спеціальності «Фармація, промислова фармація» / В. А. Георгіянц, О. С. Головченко, О. В. Колісник та ін. – Х. : НФаУ, 2023. – 37 с. (протокол ЦМР № 2 від 16.02.2023 р.)
  5. Chromatographic research methods: guidelines for students of educational program ‘Pharmacy’ / V. A. Georgiyants, N. M. Smielova, H. V. Hryhoriv, O. A. Yevtifieieva, V. A. Chornyi, H. I. Severina, V. O. Grudko – Kharkiv: National University of Pharmacy, 2023. – 34 p.
  6. Хроматографічні методи досліджень: метод. рек. для здобув. вищ. освіти освіт.-проф. прог. «Фармація» / В. А. Георгіянц, Н. М. Смєлова, Г. В. Григорів, О. А. Євтіфєєва, В. А. Чорний, Г. І. Северіна, В. О. Грудько – Харків : НФаУ, 2023. – 44 с.
  7. Фaрмaцевтичнa броматологія: метoд. рек. для здобув. вищ. освіти освіт. прогр. «Фармація» / В.A. Геoргіянц, О.С. Головченко, О.В. Колісник, О.О. Михайленко, Л.О. Петрушова, Г.І. Северіна. – Харків : НФaУ, 2021. – 29 c.
  8. Pharmaceuitical bromatology: guidelines for applicants for higher education of professional program “Pharmacy” / V.A. Georgyants, O.S. Golovchenko, O.V. Kolisnyk, O.O. Mykhailenko, L.O. Petrushova, H.I. Severina – Kharkiv : NUPh, 2021. – 29 p.
  9. Фaрмaцевтическая броматология: метoд. рек. для соиск. высш. образования образ. прогр. «Фармация» / В.A. Геoргиянц, О.С. Головченко, Е.В. Колесник, О.А Михайленко., Л.А. Петрушова, А.И. Северина– Харьков : НФaУ, 2021. – 29 c.
  10. Методичні рекомендації з контролю якості лікарських засобів. Модуль «Лікарські засоби похідні гетероциклів, алкалоїдів, вуглеводів та вітамінів» / В. А. Георгіянц [та ін.] В. А. Георгіянц І. В. Українець,  Л. В. Сидоренко,  Н. Ю. Бевз,  О. В. Горохова,  В. О. Грудько,  Г.І. Северіна, Л. О. Петрушова,  Г. О. Бур’ян,  О. В. Бевз. – Х. : Вид-во НФаУ, 2018. – 67 с.
  11. Щоденник виробничої практики з фармацевтичної хімії / В.А. Георгіянц, П О. Безуглий, Г.О. Бур’ян, О.В. Колісник, Г.І. Северіна, А.І. Абу Шарк, В.В. Гриненко, І.А. Данилова; за заг. редакцією В.А. Георгіянц. – Харків : НФаУ, 2017. – 60с.
  12. Фармацевтическая броматология : лекции / Н. В. Попова [и др.]. Н. В. Попова, П. А. Безуглый, В. А. Георгиянц, О. С. Головченко, Г. И. Северина, Г. П. Казаков, С. В. Ковалев, Д. А. Алферова – Х.: Изд-во НФаУ, 2015. – 160 с.
  13. Pharmaceutical bromatology lectures for english-speaking students / V.A. Georgiyants, P.O. Bezugly, G.O. Burian, A.I. Abu Sharkh, K.A. Taran, G.I. Severina, O.S. Golovchenko, Yu.S. Prokopenko, L.P. Savchenko, N.V. Popova; edited by V. A. Georgiyants. – Kharkiv : Publishing House of NPhAU, 2014. – 278 p.
  14. Программа, методические рекомендации и контрольные задания по фармацевтической химии (для студентов факультета ступенчатого фармацевтического образования (заочного отделения) со сроками обучения – 4.5, 2.5, 2.0 года) / Георгиянц В.А., Безуглый П.А., Украинец И.В. и др.// Харьков: Изд-во НФаУ, 2012. – 79 с.
  15. Збірник тестів з фармацевтичної хімії / Алексєєва Л.М., Бевз Н.Ю., Гриненко В.В. та інші // Методические рекомендации. Харків: Вид-во НФаУ, 2012. – 415 с.
  16. Тонкослойная хроматография в анализе синтетических пищевых красителей в продуктах питания / П.А. Безуглый, Е.А. Мамина, В.А. Георгиянц и др.// Методические рекомендации. Харьков: Изд-во НФаУ, 2012. – 23 с.
  17. Анализ антибиотиков в пищевых продуктах методом высокоэффективной жидкостной хроматографии / П.А. Безуглый, Е.А. Мамина, В.А. Георгиянц и др.// Методические рекомендации. Харьков: Изд-во НФаУ, 2012. – 21 с.
  18. Ответы к сборнику вопросов для самостоятельной работы студентов по фармацевтической химии (для подготовки к лицензионному экзамену «Крок-2» / Алексеева Л.М., Алексеева Т.В., Бевз Н.Ю. и другие // Учебное полсобие. Харьков: Изд-во НФаУ, 2012. – 96 с.

Articles in specialized foreign scientific journals

  1. Bioisosteric replacement in the search for biologically active compounds: design, synthesis and anti-inflammatory activity of novel [1,2,4]triazino[2,3-c]quinazolines / O. Grytsak, K. Shabelnyk, Severina, V. Ryzhenko, O. Voskoboinik, I. Belenichev, S. Kovalenko, V. Oksenych, O. Kamyshnyi. Pharmaceuticals. 2024. Vol.17, № 11. P.1437. https://doi.org/10.3390/ph17111437 Scopus, Web of Science, Q1
  2. Prospects for the use of sulfur-containing pteridines in toxic liver damage / N. Lohvinenko, Shvets, G. Berest, L. Nosulenko, O. Voskoboinik, H. Severina, S. Okovytyy, S. Kovalenko. Regulatory Mechanisms in Biosystems. 2024. Vol. 15, № (2). P. 374-381. https://doi.org/10.15421/022453 Scopus, Q4
  3. Vlasov S., Krolenko K., Severina H., Vlasova O., Borysov O., Shynkarenko Р., Vlasov V., Georgiyants V. Novel 4-methylthienopyrimidines as antimicrobial agents: synthesis, docking study and in vitro evaluation. Journal of Applied Pharmaceutical Science. 2023. Vol.13(04). P.105–113. https://dx.doi.org/10.7324/JAPS.2023.102631
  4. Ukrainets I., Burian A., Voloshchuk N., Taran I., Shishkina S., Severina H., Grinevich L., Sim G., Burian K., Georgiyants V. Design, synthesis and biological evaluation of novel N-alkyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides as promising analgesics. Medicinal Chemistry. 2022. 19(2). P. 174-192. https://dx.doi.org/10.2174/1573406418666220820103927
  5. Shtrygol’ S., Zalevskyi S., Mishchenko M., Shtrygol D., Severina H., El Kayal W., Georgiyants V. Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2- (2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico. Čes. slov. Farm. 2022. 71. 224-233 http://surl.li/dwofu
  6. Vyshnevska L., Severina H.I., Prokopenko Y., Shmalko A. Molecular docking investigation of anti-inflammatory herbal compounds as potential LOX-5 and COX-2 inhibitors. 2022. 69(3). P. 733-744. https://dx.doi.org/10.3897/pharmacia.69.e89400
  7. El Kayal W., Severina H., Tsyvunin V., Zalevskyi S., Shtrygol’ S., Vlasov S., Golovchenko O., Kovalenko S., Georgiyants, V. Synthesis and anticonvulsant activity evaluation of n-[(2,4-dichlorophenyl)methyl]-2-(2,4-dioxo-1h-quinazolin-3-yl)acetamide novel 1-benzylsubstituted derivatives. ScienceRise: Pharmaceutical Science. 2022. 1(35). P. 58–69. https://doi.org/10.15587/2519-4852.2022.253554
  8. Vlasov S.V., Severina H. I., Borysov O.V., Krolenko K.Y., Shynkarenko P.E., Saidov N.B., Vlasov V.S., Georgiyants V. A. Synthesis and Antimicrobial Evaluation of 2-(6-Imidazo[1,2-a]pyridin-2-yl-5-methyl-2,4-dioxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)-N-arylacetamide Derivatives. 2022, no. 1: M1331. https://doi.org/10.3390/M1331
  9. Vlasov S.V., Vlasova O.D., Severina H.I., Krolenko K.Y., Borysov O.V., Abu Sharkh A.I.M., Vlasov V.S, Georgiyants V.A. Design, Synthesis and In Vitro Antimicrobial Activity of 6-(1H-Benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-thio-3,4-dihydrothieno[2,3-d]pyrimidines. Scientia Pharmaceutica. 2021. 89(4). P. 49-64. https://doi.org/10.3390/scipharm89040049
  10. Severina H. I., Gubar S.M., Bezruk I. V., Materiienko A. S., Ivanauskas L., Bunyatyan V.A., Kovalenko S.M., Scupa O. O., Georgiyants V.A. Development and validation of HPLC determination of related substances in a novel anticonvulsant agent epimedin. Research J. of Pharmcy and Technology. 14(6). P. 3223-1. https://doi.org/10.52711/0974-360X.2021.00561
  11. Severina H. I., Skupa O.O., Voloshchuk N. I., Khairulin A. R., Georgiyants V. A. Design, synthesis, in vivo and in silico anticonvulsant activity studies of derivatives of 6-amino-4-hydroxy-2-thio-pyrimidine.. ACTA Pharmaceutica Sciencia. 2020. 58. 3. Р. 371-393. https://doi.org/23893/1307-2080.APS.05821 http://www.actapharmsci.com/abstract.php?id=675.
  12. Severina H.I., Skupa O.O., Voloshchuk N. I., Khairulin A. R., Georgiyants V. A. Synthesis, docking study, and pharmacological evaluation of S-acetamide derivatives of 4,6-dimethyl-2-thiopyrimidine as anticonvulsant agents. Journal of Applied Pharmaceutical Science. 10. 07. Р. 001-008. https://doi.org/10.7324/JAPS.2020.10701
  13. Severina H. I., Georgiyants V.A., Kovalenko S. M., Avdeeva N. V., Yarcev A. I., Prohoda S. N. Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptorsResearch Results in Pharmacology. 6(1). P. 69–82. https://doi.org/10.3897/rrpharmacology.6.52026
  14. Severina H., Bezruk I., Ivanauskas L., Georgiyants V. Development of hplc method for quantitative determination of Epimidin – new perspective АPhI with anticonvulsive activity. ScienceRise: Pharmaceutical Science. 2020. №3(25). Р. 4-11. https://doi.org/10.15587/2519-4852.2020.203181
  15. Severina H., Voloshchuk N., Saidov N., Georgiyants V.. Design, synthesis, molecular docking and anticonvulsant evaluation of 6-methyl-2-arylaminopyrimidin-4(3H)-one. ScienceRise: Pharmaceutical Science. 2020. №2 (24). P. 9-17. https://doi.org/10.15587/2519-4852.2020.200809
  16. Perekhoda L., Georgiyants V., Yeromina H., Drapak I., Lubenets V., Ieromina Z., Sych I., Severina H., Demchenko A.. The synthesis and in silico antihypertensive activity prognosis of new mannich bases containing the 1,2,4-triazole moiety. Chemistry & chemical technology.Vol. 14. №2. P. 214–220. https://doi.org/10.23939/chcht14.02.214
  17. Severina H.I., Skupa O.O., Voloshchuk N.I., Saidov N., Bunyatyan V.A., Kovalenko S.M., Georgiyants V.A.. Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio} acetamide as a promising anticonvulsant. Research Results in Pharmacology. №6(2). Р. 27–41. https://doi.org/10.3897/rrpharmacology.6.53332
  18. Bunyatyan N. D., Severina H. I., El Kayal W.M., Zalevskyi S. V., Shtrygol S. Yu., Abu Shark A., Tsyvunin V. V., Kompantsev D. V., Shevchenko A. M., Kovalenko S. N., Georgiyants V. A., Ogay M. A., Khadzhieva Z. J. Synthesis and anticonvulsant activity of new 2-(4-oxo-2-thioxo-1,4-dihydro-3(2H)quinazolinyl)acetamides. Pharmaceutical Chemistry Journal. Vol. 54. № 1. 2020. P. 1-8. https://doi.org/10.1007/s11094-020-02147-5 https://link.springer.com/article/10.1007/s11094-020-02147-5
  19. Severina H.I., Skupa O.O., Voloshchuk N.I., Suleiman M.M., Georgiyants V.A. Synthesis and anticonvulsant activity of 6-methyl-2-((2-oxo-2-arylethyl)thio)pyrimidin-4(3Н)-one derivatives and products of their cyclization. Pharmacia. Vol. 66. №3. P. 141-146. https://doi.org/10.3897/pharmacia.66.e38137
  20. El Kayal W.M., Shtrygol S.Y., Zalevskyi S.V., Shark A.A., Tsyvunin V.V., Kovalenko S.M., Bunyatyan N.D., Perekhoda L.O., Severina H.I., Georgiyants V.A. Synthesis, in vivo and in silico anticonvulsant activity studies of new derivatives of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)acetamide. European Journal of Medicinal Chemistry. 2019. Vol. 180. P. 134-142. https://doi.org/10.1016/j.ejmech.2019.06.085
  21. Severina Н., Skupa O., Khairulin A., Voloshchuk N., Georgiyants V. Synthesis and anticonvulsant activity of 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one acetamides. Journal of Applied Pharmaceutical Science. Vol. 9(02). P. 012-019, https://doi.org/10.7324/JAPS.2019.90202
  22. Severina A.I., Kavraiskyi D.P., Kovalevska I.V., Shtrygol S.Yu., Ruban E.A., Georgiyants V.A. Dependence of anticonvulsant activity of 1-aryl-1, 5-dihydro-4H-pyrazole (3,4-d) pyrimidine-4-one derivatives on biopharmaceutical factors. International Journal of Basic & Clinical Pharmacology. 2017. Vol 6. № 7. P. 1552-1559. DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20172715
  23. Severina A. I., Georgiyants V. А., Shtrygol S. Yu., Kavraiskyi D. P. Synthesis of N-substituted derivatives of 1-(4-methoxyphenyl)-1,5-dihydro-4H- pyrazolo[3,4-d]pyrimidin-4-one as potential anticonvulsants. Scripta scientifica pharmaceutica. 2016. Vol. 3. № 2. P. 36-40.  http://dx.doi.org/10.14748/ssp.v3i2.1408
  24. Kushniruk V.M., Severina A.I., Georgiyants V.A. Standardization of the Active Pharmaceutical Ingredients Industrial Synthesis Technology. Acta Chim Pharm Indica. 2017. 7(2).  Р. 1-11.

Articles in specialized scientific journals of Ukraine:

  1. Vlasov S. V., Borysov O. V., Severina H. I., Kovalenko S. M., Osolodchenko T. P., Vlasov V. S., Georgiyants V. A. The synthesis, antimicrobial activity and docking studies of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidin 4(3H)-ones with acetamide and 1,2,4-oxadiazol-5-ylmethyl substituents. Журнал органічної та фармацевтичної хімії. 2021. Т. 19. 3(75). 15-20. https://doi.org/10.24959/ophcj.21.240775
  2. Каврайський Д.П., Штриголь С.Ю., Георгіянц В.А., Северіна Г.І. Скринінгове дослідження нових похідних піразоло[3,4-d]піримідин-4-ону на проти судомну активність. Фармакологія та лікарська токсикологія. 2016. № 3(49). С. 16-27
  3. Д. П. Каврайський, С. Ю. Штриголь, В. А. Георгіянц, Г. І. Северіна Експериментальне вивчення спектру протисудомної активності нових похідних піразоло[3,4-D]піримідин-4-ону. Scientific Journal «ScienceRise: Pharmaceutical Science». №1(1). C. 10-17. https://doi.org/10.15587/2519-4852.2016.70528
  4. Каврайський Д.П., Штриголь С.Ю., Цивунін В.В., Штриголь Д.В., Северіна Г.І., Георгіянц В.А. Перспективний антиконвульсант 1-(4-метоксифеніл)-5-{2- [4-(4-метоксифеніл)піперазин-1-іл]-2-оксоетил}-1,5-дигідро-4Н-піразоло[3,4-d]піридин-4-он має протизапальну та знеболювальну активність та позбавлений адиктивного потенціалу. Український журнал клiнiчної та лабораторної медицини. 2016. Т. 11, № 3. С. 52-62

Educational components taught by Doctor of Science Hanna Severina:

  • Pharmaceutical chemistry
  • Standardization of medicines
  • Pharmaceutical bromatology
  • Industrial Pharmaceutical Practice in Pharmaceutical Chemistry

She has 16 years of teaching experience in higher education institutions of III-IV accreditation levels and at the National University of Pharmacy.

Hobby. Hanna is fond of playing tennis and skiing, and finds inspiration by traveling all over the world.

  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA
  • Hanna SEVERINA