The Department of Pharmaceutical Chemistry was founded in 1921 at the Kharkiv Chemical-Pharmaceutical Institute, headed by Doctor of Pharmaceutical and Chemical Sciences, Professor Mykola Ovksentiyovych Valyashko.

Until 1937, the department combined pharmaceutical and forensic chemistry, pharmacognosy, and the synthesis of pharmaceutical and industrial drugs. To perform the research work, a research laboratory was established, which carried out the research, performed the dissertations by post-graduate students and teachers of the department. After the separation of pharmacognosy and forensic chemistry in 1937, the department was headed by Associate Professor T. S. Kusner, but M.O. Valyashko remained the consultant and supervisor.

• Mykola Valyashko, the first rector of Kharkiv Chemical-Pharmaceutical Institute, Professor, Doctor of Chemistry and Pharmacy. The direction of scientific research is the study of the chemistry of medicinal substances and the study of their structure according to the absorption spectra in the ultraviolet region; study of chemical properties of adonin, rutin, robinin, kaempferol, components of buckthorn fruit; samples of essential oils from Ukrainian plants. The scientist worked on the development of ideas of O.M. Butlerov and V.V. Markovnykov.
• Mykola Krasovskyy, Professor, Doctor of Pharmaceutical Sciences. He paid great attention to methodological and organizational work in the system of higher pharmaceutical education, established a school in the field of chemistry of herbal medicines, had more than 20 followers, published more than 50 scientific works and a textbook on analytical chemistry.
• Vasyl Blyznyukov, Professor, Doctor of Pharmaceutical Sciences. Invented a new spectrograph for the quantitative study of the ultraviolet spectra, studied the absorption spectra of pyridine and its derivatives to establish the interaction of cyclic nitrogen with substituents in the pyridine nucleus. He has published about 100 scientific works, prepared 10 doctors and 7 candidates of science.
• Oleksiy Sukhomlinov, Professor, Doctor of Pharmacy. The main direction is research was the acridine derivatives. He is the author of about 146 scientific works and teaching guides, including seven certificates of invention. Prepared seven candidates of sciences (PhD) and two doctors of sciences.
• Vira Shtuchna, Associate Professor, PhD of Pharmacy. Scientific direction was the synthesis and investigation of biologically active compounds among acridine derivatives. Author of about 40 scientific and educational works.
• Illarion Depeshko, Professor, Doctor of Pharmacy. The direction of scientific research was the study of the absorption spectra and structure of heterocyclic compounds among the pyrazole, pyrazoline and thiazole derivatives. The author of more than 100 scientific and and teaching guides, including 28 certificates of invention.
• Petro Bezugly, Professor, Doctor of Pharmacy, Honored Worker of Science and Technology of Ukraine, Academician of the Academy of Higher Education of Ukraine. The direction of scientific research was the development of preparative methods of targeted synthesis of biologically active compounds among the derivatives of indolinones, dicarboxylic acids and quinolines. The author of about 300 scientific and teaching guides, including 11 patents of invention, 117 certificates of invention, a textbook, and three textbooks.
• Victoriya Georgiyants, Honored Professor of NUPh, Doctor of Pharmacy, Academician of the Academy of Higher Education of Ukraine, Professor. The direction of scientific research is the directed search for promising substances of synthetic and natural origin in order to create drugs for the treatment of epilepsy; the molecular modeling of potential anticonvulsants; the research in the field of standardization of drugs for industrial and extemporal production. The author of more than 300 scientific and educational works, including a textbook, 10 teaching guides, two of them in English.

Lidiya Sokol (1950-1983), Nataliya Solonska (1954-1984), Oleksij Suxomlinov (1961-1974), Oleksandr Gajdukevych (1967-1983), Svitlana Leonova (1967-2018), Valerij Bolotov (1968-1984), Gennadij Petyunin (1970-1986), Ivan Bondarchuk (1970-2008), Vladkor Chubenko (1973-1977), Yevgen Levitin (1975-1978), Svitlana Taran (1976-2004), Volodymyr Triskach (1978-1996), Sergij Isayev (1980-2004), Lyubov Alyeksyeyeva (1983-2013), Lina Perexoda (1986-2004), Vadim Zubkov (1988-2004), Tina Prokopenko (1993-1997), Olena Mamina (2009-2013), Igor Ukrainets (1982-2020), Iryna Danylova (2011-2020).

Nataliia Bevz (since 1978), Olha Horokhova (since 1981), Nataliia Harna (since 1981), Ihor Ukrainets (since 1982), Volodymyr Hrudko (since 1983), Tetiana Aleksieieva ( since 1986), Vasyl Hrynenko (since 1987), Viktoriia Georgiyants (since 1987), Olha Yevtifieieva (1991-1995, since 2016), Liudmyla Sydorenko (since 1994); Kateryna Taran (since 1998), Abu-Shark Amzhad I.M. (since 1999), Olha Holovchenko (since 2001), Lidiia Petrushova (since 2002), Hanna Severina Ivanivna (since 2003), Olena Kolesnyk (since 2003), Hanna Burian (since 2003), Iryna Danylova (since 2011), Oksana Koretnik (since 2015), Nataliia Smielova (since 2018).

2001, 2013 – teaching guide “Pharmaceutical Analysis” (in Ukrainian), (edited by P.O .Bezugly).
2002, 2006 – teaching guide “Pharmaceutical Chemistry” (in Ukrainian) (edited by P.O. Bezugly).
2008, 2011, 2017 – textbook”Pharmaceutical Chemistry” (in Ukrainian) (edited by P.O. Bezugly) (“Best edition of the year” according to the Academy of Higher Education of Ukraine, 2018)
2013 – teaching guide “Pharmaceutical Chemistry. Analysis of drugs of biotechnological production”(V.A. Georgiyants, P.O. Bezugly, L.O. Petrushova, etc.).
2013 – teaching guide “Pharmaceutical chemistry. Lectures for English-speaking students” (edited by V.A. Georgiyants, P.O. Bezugly).
2014 – teaching guide “Pharmaceutical Bromatology” (in Russian) (edited by V.A. Georgiyants).
2015 – teaching guide “Pharmaceutical bromatology” (edited by V.A. Georgiyants) (2nd place in the nomination “Best teaching guide” in the competition “Best educational and methodological development of the year”, 2017)
2015 – teaching guide “Tests in pharmaceutical chemistry” (P.A. Bezugly, I.S. Gritsenko, V.A. Georgiyants, etc.).
2016 – teaching guide “Pharmaceutical Analysis” (in Russian), (edited by P.A. Bezugly).
2017 – teaching guide “Pharmaceutical Bromatology” (in Ukrainian) (edited by V.A. Georgiyants).
2017 – textbook “Pharmaceutical Chemistry” (in Russian) (edited by P.A. Bezugly).
2018 – teaching guide “Pharmaceutical analysis” (edited by V.A. Georgiyants).

From 1921 – the scientific direction of Prof. Valyashko M. was the study of the organic compounds of synthetic and plant origin absorption spectra and structure (1 doctoral, 16 candidate theses).
From 1980 – the scientific direction of Prof. Bezugly P. was the development of preparative methods for targeted synthesis of biologically active substances among derivatives of indolinones, dicarboxylic acids and 2-oxo-4-hydroxyquinoline (3 doctoral and 17 candidate theses). Bezugly P. was the author of 11 patents of invention, 117 certificates of invention, and 240 scientific articles.
From 1993 – the scientific direction of Prof. Ukrainets I. was the synthesis, reactivity and biological activity in a number of derivatives of malonic acid, 2-oxo-4-hydroxyquinoline and 2,2-dioxo-1H-2λ6,1-benzothiazine (3 doctoral and 21 candidate theses). Ukrainets I. was the author of more than 300 scientific articles, among them 180 articles were published in the international journals (Chemistry of Heterocyclic Compounds, Tetrahedron Letters, Acta Crystallo-graphica, Spectrochimica Acta, Journal of Analytical Chemistry, Tetrahedron, etc.), more than 70 certificates and patents of invention.
Since 2005 – the scientific direction of Prof. Georgiyants V. is the molecular modeling and targeted search for anticonvulsants; substantiation of standardization parameters, development and validation of methods of quality control of medicines of industrial and extemporal production (7 doctoral and 18 candidate theses). Georgiyants V. is the author and co-author of more than 700 scientific works, including 350 scientific articles, 12 certificates of invention, 26 patents of  inventions and 48 patents of utility models of Ukraine and 30 information letters.
Since 2016 – the research direction Assoc. Prof. Bevz N. is the development and validation of methods of quality control of medicines of synthetic and natural origin (2 candidate theses). Bevz N. is the author and co-author of about 200 scientific articles, 23 certificates and patents of invention.
Employees of the department took part in the development of 21 medications of different pharmacological action.

1921 – the Department of Pharmaceutical Chemistry was established.
1921-1937 – the department combined pharmaceutical and forensic chemistry, pharmacognosy and the synthesis of pharmaceutical and galenic drugs. During these years, the lectures on pharmaceutical chemistry were given in III-IV years of study. Students had four hours of lectures, six to eight hours of practical classes, and two hours of seminars a week. During these years, the research work had two main directions:
1) development of medications from plant raw materials, the technology for their manufacture and methods of analysis;
2) synthesis and study of structure-activity relationship of new substances.
1925 – a research laboratory was established to train researchers in pharmaceutical specialties.
1935 – Professor Blyznyukov V. invented a new spectrograph for the quantitative study of ultraviolet spectra.
1941-1946 – the department worked in the evacuation in Semipalatinsk, Professor Krasovskyy M. was the head of the department.
1946 – the department came back from the evacuation and resumed its work. The teachers of the department together with students repaired the premises.
1964-1970 – the department was headed by Associate Professor Sukhomlinov O. Under his leadership, the research on the synthesis and study of new biologically active compounds among aromatic hydrazides, benzolactams and alkyloxynates of adamantylammonium was carried out.
1970-1976 – Shtuchna Vira Petrivna was the head of the department. The main scientific direction of her work was the synthesis, study and search of biologically active compounds among acridine derivatives.
1976-1986 – the department was headed by Professor Depeshko Illarion Trokhymovych. The scientific direction of his activity was the synthesis and spectroscopic studies of biologically active substances and drugs, derivatives of phenylhydrazine, pyrazoline and thiazole. He was the author of more than 100 scientific works, 28 certificates of inventions, he advised 5 candidate theses.
1981 – Prof. Bezugly Petro Ovksentiyovych got the award of Excellence in health care.
1983 – Prof. Bezugly Petro Ovksentiyovych got the award of Science and Technology of Ukraine.
1985-2009 – the head of the department was Professor Bezugly Petro Ovksentiyovych,. The author’s team of the department has prepared textbooks “Pharmaceutical Chemistry” and “Pharmaceutical Analysis”.
1994 – the department began training engineers-technologists at the Faculty of Industrial Pharmacy, which was established in January 1992.
1999 – the staff of the department began training students in “Marketing and Business Economics”. A specialization course has been created for 5th year students “Quality control of food products and food additives”.
1999-2000 – standard work programs in pharmaceutical and cosmetic chemistry, as well as in medical chemistry for the specialties “Technology of perfumes and cosmetics” and “Clinical Pharmacy” were created.
2001 – the staff of the department began training students in the specialty “Management of Organizations”.
2005 – the Department of Pharmaceutical Chemistry was divided into two departments – “Medical Chemistry” and “Pharmaceutical Chemistry”.
2005-2010 – cooperation of scientists of the department with the Institute of Infectious and Allergic Diseases (USA).
2005-2015 – scientific cooperation with the National Cancer Institute of the United States.
2005 – prof. V.A. Georgians got the award “Excellence  in education”.
2006 – prof. P.O. Bezugly got the award-“For Merits of the III degree”.
2006 – the cooperation agreement with the Lithuanian University of Health Sciences and the Department.
2008 – prof. Ukrainets IV was awarded a diploma of the International Foundation “Scientific Partnership” of Moscow State University named after M.V. Lomonosov.
2008 – prof. V.A. Georgiyants is an official observer from the NUPh in the US Pharmacopoeia and an expert in the US Pharmacopoeia.
2010 – the department was headed by Professor Georgiyants Victoriya Akopivna.
2010 – the grants for internships under the visiting scientist program on the basis of the US Pharmacopoeia were awarded to Assoc. Prof. Zdorik O.A. and Prokopenko Yu.S.
2011 – basic department in teaching disciplines “Pharmaceutical Chemistry” of the educational program “Industrial Pharmacy” and “Standardization of medicines” of the educational program “Pharmacy”.
2013 – prof. P.O.. Bezugly is an honored professor of NUPh.
2015 – prof. V.A. Georgiyants is an honored professor of NUPh.
2015 – prof. I.V. Ukrainets was awarded a diploma and a gold medal “100 years of Professor A.N. Costa by ”Russian Chemical Society named after D.I. Mendeleev for special achievements in the chemistry of heterocyclic compounds.
2016 – prof. V.A. Georgiyants – Honored Worker of Science and Technology of Ukraine; prof. І.V. Ukrainets – Honored Professor of NUPh.
2017 – prof. V.A. Georgiyants is an academician of the Academy of Higher Education of Ukraine.
2018 – prof. P.O. Bezugly is an academician of the Academy of Higher Education of Ukraine.
For the first time, the first round of the Ukrainian Students’ Contest in Pharmaceutical Chemistry was organized and held.
The department won the 4th place in the ranking of NUPh departments for the 2017/2018 academic year.
2019 – prof. V.A. Georgiyants took part in the academic exchange with Medical University (Varna, Bulgaria).
Participation of teachers of the department in the programs as visiting professors: Prof. Georgiyants V.A. (Yemen, 2003; Tajikistan, 2013; Kazakhstan, 2015), Assoc. Prof. Grudko V.О. and Assoc. Prof. Bevz N.Yu. (Kazakhstan, 2013), Prof. Ukrainets IV, Assoc. Prof.  Sidorenko L.V. (Mexico, 2016), Assoc. Prof. Taran K.A. (Mexico, 2018).
Participation in the Erasmus + program – academic exchanges postgrad. Migal A.V. (2016), Prof. Georgiants V.A. (2017, 2019), postgrad.. Bezruk I.V. (2018, 2019), Assoc. Burian G.O.(2019).
Lectures of foreign professors: Alex Fichter (US Pharmacopoeia, 2016), prof. L. Ivanauskas (Lithuanian University of Health Sciences, 2017, 2018, 2019).