Публікації кафедри

Наукові публікації Кафедри фармацевтичної хімії

2020 рік

  • Combined Approach to the Choice of Chromatographic Methods for Routine Determination of Hederacoside C in Ivy Leaf Extracts, Capsules, and Syrup / Bezruk, I., Kotvitska, A., Korzh, I., Materiienko, A., Gubar, S., Budanova, L., Georgiyants, V. // Scientia Pharmaceutica, 2020, 88(2), 24.  doi.org/10.3390/scipharm88020024
  • Comparative Investigation of Amino Acids Content in the Dry Extracts of Juno bucharica, Gladiolus Hybrid Zefir, Iris Hungarica, Iris Variegata and Crocus Sativus Raw Materials of Ukrainian Flora / Mykhailenko, O.; Ivanauskas, L.; Bezruk, I.; Lesyk, R.; Georgiyants, V. // Sci. Pharm. 2020, 88, 8. doi.org/10.3390/scipharm88010008
  • Biological properties of two enantiomorphic forms of N-(2,6-dimethylphenyl)-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, a structural analogue of piroxicam /Shishkina, S.V.Ukrainets, I.V.Vashchenko, O.V., . Petrushova, L.A.Sim, G. // Acta Crystallographica Section C: Structural Chemistry, 2020, 76, с. 69-74. doi.org/10.1107/S2053229619016450
  • Methyl 4-hydroxy-2,2-dioxo-1h-2λ6,1-benzothiazine- 3-carboxylate and its analogs modified in the benzene moiety of the molecule as new analgesics /Ukrainets, I.V.Petrushova, L.A.Shishkina, S.V.Torianyk, I.I.Davidenko, A.A. // Scientia Pharmaceutica, 2020, 88(1), 10 https://doi.org/10.3390/scipharm88010010
  • Crystal habits and biological properties of N-(4-trifluoromethylphenyl)-4-hydroxy-2, 2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide / Ukrainets, I.V.Petrushova, L.A.Fedosov, A.I., .Sidorenko, L.V.Sim, G. // Scientia Pharmaceutica, 2020, 88(1), 1 https://doi.org/10.3390/scipharm88010001
  • Methyl 5-chloro-4-hydroxy-2,2-dioxo-1H-2k6,1-benzothiazine-3-carboxylate: Structure and Hirshfeld surface analysis / Shishkina, S.V.Petrushova, L.A.Burian, K.O.Fedosov, A.I.Ukrainets, I.V. // Acta Crystallographica Section E: Crystallographic Communications, 2020, 76, с. 1657-1660. doi.org/10.1107/S2056989020012566
  • Effect of ecological factors on the accumulation of phenolic compounds in Iris species from Latvia, Lithuania and Ukraine. / Mykhailenko, O., Gudžinskas, Z., Kovalyov, V., Desenko, V., Ivanauskas, L., Bezruk, I.,Georgiyants, V. // Phytochemical Analysis. – 2020, 31(5), с. 545-563 doi.org/10.1002/pca.2918
  • HPLC method for simultaneous determination of impurities and degradation products in Cardiazol / Drapak, I., Zimenkovsky, B., Ivanauskas, L., Bezruk, I., Perekhoda, L., Muzychenko, V., Demchuk, I. (2020). // Pharmacia, 2020, 67, 29-37. doi: 10.3897/pharmacia.67.e37004
  • Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptors / Severina, H. I., Georgiyants, V. A., Kovalenko, S. M., Avdeeva, N. V., Yarcev, A. I., Prohoda, S. N. // Research Results in Pharmacology, 2020, 6, 69-82. doi: 10.3897/rrpharmacology.6.52026
  • Standard operating procedure of Ukrainian Saffron Cultivation According with Good Agricultural and Collection Practices to assure quality and traceability / Мykhailenko О., Desenko V., Ivanauskas L.,  Georgiyants V. // Industrial Crops and Products. 2020. 151, 112376-112387  DOI: https://doi.org/10.1016/j.indcrop.2020.112376
  • Synthesis and anticonvulsant activity of new 2-(4-oxo-2-thioxo-1,4-dihydro-3(2H)quinazolinyl)acetamides / N. D. Bunyatyan, H. I. Severina, El Kayal Wassim Mokhamad, S. V. Zalevskyi, S. Yu. Shtrygol, Amjad Abu Shark, V. V. Tsyvunin, D. V. Kompantsev, A. M. Shevchenko, S. N. Kovalenko, V. A. Georgiyants, M. A. Ogay, Z. J. Khadzhieva //  Pharmaceutical Chemistry Journal, Vol. 54, No. 1, 1-8. 2020. doi 10.1007/s11094-020-02147-5
  • The synthesis and in silico antihypertensive activity prognosis of new mannich bases containing the 1,2,4-triazole moiety / L. Perekhoda, V. Georgiyants, H. Yeromina, I. Drapak, V. Lubenets, Z. Ieromina, I. Sych, H. Severina, A. Demchenko // Chem. Chem. Technol., 2020, Chemistry Vol. 14, No. 2, pp. 214–220 https://doi.org/10.23939/chcht14.02.214
  • Bunyatyan, N.D., Severina, H. I.,Mokhamad, E.K.W. S.V. Zalevsky, S.Yu. Shtrygol, AmzhadabuShark, V.V. Tsyvunin, D.V. Kompansev, A.M. Shevchenko, S.N. Oh, Z.D.Hadzhieva. SynthesisandAnticonvulsantActivityofNew 2-(4-Oxo-2-Thioxo-1,4-Dihydro-3(2h)-Quinazolinyl)Acetamides. Pharm.Chem.J. 54, 1–6. 2020. https://doi.org/10.1007/s11094-020-02147-5
  • The synthesis and in silico antihypertensive activity prognosis of new mannich bases containing the 1,2,4-triazole moiety / L. Perekhoda, V. Georgiyants, H. Yeromina, I. Drapak, V. Lubenets, Z. Ieromina, I. Sych, H. Severina, A. Demchenko // Chem. Chem. Technol., 2020, Chemistry Vol. 14, No. 2, pp. 214–220 https://doi.org/10.23939/chcht14.02.214
  • Bunyatyan, N.D., Severina, H. I.,Mokhamad, E.K.W. S.V. Zalevsky, S.Yu. Shtrygol, AmzhadabuShark, V.V. Tsyvunin, D.V. Kompansev, A.M. Shevchenko, S.N. Oh, Z.D.Hadzhieva. SynthesisandAnticonvulsantActivityofNew 2-(4-Oxo-2-Thioxo-1,4-Dihydro-3(2h)-Quinazolinyl)Acetamides. Pharm.Chem.J. 54, 1–6. 2020. https://doi.org/10.1007/s11094-020-02147-5
  • Development of HPLC method for quantitative determination of epimidin – new perspective аphi with anticonvulsive activity / Hanna Severina, Ivan Bezruk, Liudas Ivanauskas, Victoriya Georgiyants // ScienceRise: Pharmaceutical Science. – 2020. – №. 3 (25). – С. 5-11. doi.org/10.15587/2519-4852.2020.203181
  • Development and validation of the method for simultaneous determination of benzydamine hydrochloride and methylparaben in dosage form by HPLC / Vasyl Chornyi, Olga Chorna, Victoriya Georgiyants // ScienceRise: Pharmaceutical Science. – 2020. – №. 3 (25). – С. 12-19. https://doi.org/10.15587/2519-4852.2020.206579

2019 рік

  • Synthesis and anticonvulsant activity of 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one acetamides / H. Severina, O. Skupa, A. Khairulin, N. Voloshchuk, V. Georgiyants. Journal of Applied Pharmaceutical Science. 2019. Vol. 9. № 02. Р. 012-019. doi: 10.7324/JAPS.2019.90202
  • Prokopenko Yu. S., Perekhoda L. O., Georgiyants V. A. Docking studies of biologically active substances from plant extracts with anticonvulsant activity Journal of Applied Pharmaceutical Science. 2019. Vol. 9. № 01. Р. 066-072. doi: 10.7324/JAPS.2019.90110
  • Vladymyrova I., Georgiyants V., Savelieva E. Pharmacotherapeutic action analysys of mineral substances of medicinal plants, which are used in thyroid gland diseases. Bulletin of national academy of sciences of the republic of Kazakhstan. 2019. Vol. 1. № 377. Р. 6 – 13. doi: 10.32014/2018.2518-1467
  • Synthesis, in vivo and in silico anticonvulsant activity studies of new derivatives of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)acetamide / Wassim Mokhamad El Kayal, S. Yu Shtrygol, S. V. Zalevskyi, A. abu Shark, V. V. Tsyvunin, S. M. Kovalenko, N. D. Bunyatyan, L. O. Perekhoda, H. I. Severina, V. A. Georgiyants. European Journal of Medicinal Chemistry. 2019. Vol. 180. P.134-142. doi: 10.1016/j.ejmech.2019.06.085
  • Biologically active compounds and pharmacological activities of species of the genus Crocus: A review / O. Mykhailenko, V. Kovalyov, O. Goryacha, L. Ivanauskas, V. Georgiyants. Phytochemistry. 2019. Vol. 162. P.56-89. doi: 10.1016/j.phytochem.2019.02.004
  • Development of assay method for the determination of iodine-containing organic compounds by high-performance liquid chromatography // I. N. Vladymyrova, V. A Georgiyants, V. I. Husarov, T. S. Tishakova, D. S. Kharchenko. Functional Materials. 2019. Vol. 26(3). P. 643-647. doi: 10.15407/fm26.03.643
  • Molecular and crystal structure of 5,9-dimethyl-5H-pyrano[3,2-c:5,6-c′]bis[2,1-benzothiazin]-7(9H)-one-6,6,8,8-tetroxide dimethylformamide monosolvate / Andrii Rybalka, Svitlana Shishkina, Igor Ukrainets, Lyudmila Sidorenko, Galina Sim //Acta Crystallographica Section Е. — 2019. — Vol. 75. – P. 1076-1078. doi: 10.1107/S2056989019008788
  • The Crystal Structure of N-(1-Arylethyl)-4-methyl- 2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides as the Factor Determining Biological Activity Thereof / Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Irina A. Danylova, Galina Sim // Sci. Pharm. – 2019 – Vol. 87, Iss. 2. – 10. doi: 10.3390/scipharm87020010
  • Synthesis and Regularities of the Structure – Activity Relationship in a Series of N-Pyridyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides / Igor V. Ukrainets, Anna A. Burian, Ganna M. Hamza, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Kateryna O. Burian, Galina Sim // Sci. Pharm. – 2019 – Vol. 87, Iss. 2. – 12. doi: 10.3390/scipharm87020012
  • Synthesis and anticonvulsant activity of 6-methyl-2-((2-oxo-2-arylethyl)thio)pyrimidin-4(3Н)-one derivatives and products of their cyclization/ [H. I. Severina, O.O. Skupa, N. I. Voloshchuk, M. M. Suleiman, V.A. Georgiyants]// Pharmacia. – 2019. – Vol. 66. – №3. – p. 135-139. doi: 10.3897/pharmacia.66.e38137
  • Molecular Conformations and Biological Activity of N-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides / [Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lina A. Grinevich, Vasyl V. Grynenko, Galina Sim] // Sci. Pharm., 2018.- 86(50). – 1-27 p. https://doi.org/10.3390/scipharm86040050
  • Polymorphic modifications of N-(4-Methoxyphenyl)-6-hydroxy-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxamide possessing strong diuretic properties / S.V.Shishkina, I.A. Levandovski, I.V.Ukrainets, L.V. Sidorenko, L.A. Grinevich, I.B. Yanchuk // Acta Crystallographica Section C: Structural Chemistry — 2018. — Vol. 74. – P. 1759–1767. https://doi.org/10.1107/S2053229618016352
  • Selection of the optimal conditions for analysis of plant active pharmaceutical inulin ingredients by thin-layer chromatography to develop the draft for the national monograph “Inulin”‘ / N.M. Smielova, S.M. Gubar, O.A. Yevtifieieva, E.M. Bezchasnyuk // Research Journal of Pharmacy and Technology. – 12 (6). – 2019. – P. 2862-2870. doi: 10.5958/0974-360X.2019.00482.7
  • Simultaneous determination of benzydamine hydrochloride, methylparaben and peppermint oil in a spray dosage form by gas chromatography / V.A. Chornyi, V.A.. Georgiyants, S.N. Gureyeva, O.V. Chorna. // International Journal of applied Pharmaceutics. 2019. Vol. 11. № 6. P. 147-153. doi : 10.22159/ijap.2019v11i6.32918